Garlic
25,46,47].
Garlic
(Allium sativum) intake of garlic as a therapeutic agent has been practiced since past several decades to treat numerous illnesses. It encompasses hundred or more biologically beneficial secondary metabolites, such as alliin, alliinase, allicin etc. Garlic oil comprises of an amino acid identified as Alliin, which is transformed to Allicin once its bulbs are crushed. Allicin is a predecessor to numerous sulphur comprising compounds that are accountable for the taste, aroma as well as its pharmacological properties. Ajoene, another sulphur holding compound, present in garlic oil, impedes mutagenesis while selenium act as a cellular antioxidant. Researches have also discovered the existence of bioflavonoids cyanidin and quercetin, which are liable for antioxidant characteristic of garlic [43-45]. The antitumor property of Garlic is attributed to its high level of a wide-ranging diversity of organic sulfides and polysulfide�s. It is known to augment action of the immune system by activating lymphocytes and macrophages to kill cancer cells. It is also identified to interrupt the metabolism of tumor cells [32].
Moreover, garlic prevents creation as well as development of cancer by increasing action of the natural killer cells and the macrophages. Researchers have discovered that garlic enhances amount of the suppressor T cells and turns the lymphocytes further cytotoxic to tumor cells. It also restrains metastases by averting union or adhesion of the circulating tumor cells to the blood vessels. The ripened extract of garlic shields DNA from the harmful influence of carcinogens, surges activity of detoxifying enzymes, hustles up elimination of chemical carcinogens and boost body�s immune system. Further, (mature garlic extract) it is known to prevent development of several tumors including those of the breast, lungs, stomach, colon and bladder. An investigation done at the National Medical Centre and Hospital in Japan has shown that the Garlic extract lessens complications of radiotherapy and chemotherapy as well [25,46,47].
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